Thor Ole Gulsrud

Associate Professor, Stavanger University College - Signal Processing Group

Texture analysis of digital mammograms

Breast cancer is a leading cause of cancer deaths among women. For women in Norway and in the other developed countries, it is also the most frequently diagnosed cancer. In 1992, about 2100 new cases of breast cancer were detected in Norway, and in the same year 17\% of all cancer deaths among women were caused by this type of cancer disease. Early detection is the most effective way to reduce mortality, and mammographic screening is currently the best method for early detection. An increasing number of countries have started mass screening programs which have resulted in a large increase in the numbers of mammograms requiring interpretation. In the interpretation process radiologists carefully search each image for any visual sign of abnormality.

Taber and Dean have classified the visual signs for which radiologists search during mammographic screening into three basic categories; circumscribed masses, stellate lesions and calcifications. From a texture point of view the ideal case would be that each category represents a well defined texture class, making the interpretation an easy task. However, a wide variability in tumor appearance exists. In addition, there is often a visual similarity of some tumors to normal structures in dense and fatty-glandular breasts. As a consequence, radiologists often find the task of interpretation difficult. It is not uncommon that in many centers films are studied by two radiologists in an attempt to reduce error rates. To improve the accuracy of interpretation, a variety of computer based aids have been proposed. The aim of these aids may be to detect and prompt specific signs of abnormality or to distinguish between benign and malignant tumors.

Ideally, we would like to construct a system in which all forms of abnormality are automatically correctly detected and classified. However, the current state of the art in mammographic image analysis renders this a long-term goal. Thus, our main goal is to design computer-based aids which will be useful in their own right, but will also eventually contribute to a completely automated system.


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